秦国政 研究组

秦国政,男,博士,研究员,博士生导师。
2000年毕业于四川大学生物系,2004年在中国科学院植物研究所获博士学位,毕业后留所工作至今,先后任助理研究员、副研究员和研究员。2006年至2007年在美国Arizona State University做博士后研究。主要从事果实品质保持的生物学基础及调控方面的研究,在果实成熟和品质调控的重要基因筛选、基因功能研究以及果实品质保持技术的研发等方面取得了系列进展。迄今发表论文80余篇,其中20余篇(第一或通讯作者)发表在Genome Biology、Plant Journal、Plant Physiology、New Phytologist、Molecular Plant-Microbe Interactions、Molecular & Cellular Proteomics等国际主流杂志上。主持了国家自然科学基金青年基金、面上项目、国家杰出青年科学基金、国家重点基础研究发展计划(973计划)课题、国家重点研发计划子课题等科研项目。2013年获国家技术发明奖二等奖(排名第三)及中国科学院卢嘉锡青年人才奖,2016年获北京市科学技术奖二等奖(排名第二),2019年获“国家杰出青年科学基金”资助。现任Scientia Horticulturae 副主编、Journal of Integrative Plant Biology 编委、The Innovation 青年编委、《植物学报》编委。 

联系方式:E-mail:gzqin@ibcas.ac.cn; 电话:010-62836970 

主要研究方向和内容 
以番茄和草莓为主要研究材料,解析果实成熟和衰老过程中色泽、风味等品质形成的分子机制及其调控基础,为培育高品质、耐贮藏的果实品种提供依据。同时,也为果实采后品质保持和贮藏保鲜技术的研发奠定基础。研究内容包括:鉴定在果实品质形成和保持过程中发挥重要作用的基因/蛋白质,分析它们对植物激素、环境条件的响应机制;综合利用分子生物学、细胞生物学和遗传学等技术,从转录和转录后调控、翻译调控、翻译后修饰等角度解析重要基因/蛋白质对果实品质的调控机制。 

研究组成员: 
王豫颖   副研究员 

研究论文(#代表同等贡献;*代表通讯作者) 

2022

Leilei Zhou, Guangtong Gao, Renkun Tang, Weihao Wang, Yuying Wang, Shiping Tian, Guozheng Qin*. 2022. m6A-mediated regulation of crop development and stress responses. Plant Biotechnology Journal, online ahead of print, doi: 10.1111/pbi.13792.

2021

Leilei Zhou#, Renkun Tang#, Xiaojing Li, Shiping Tian, Bingbing Li, Guozheng Qin*2021. N6-methyladenosine RNA modification regulates strawberry fruit ripening in an ABA-dependent manner. Genome Biology, 22: 168.

Weihao Wang, Peiwen Wang, Xiaojing Li, Yuying Wang, Shiping Tian, Guozheng Qin*2021.  The transcription factor SlHY5 regulates the ripening of tomato fruit at both the transcriptional and translational levels. Horticulture Research, 8: 83.

Yuying Wang#, Peiwen Wang#, Weihao Wang, Lingxi Kong, Shiping Tian, Guozheng Qin*. 2021. Genome-wide binding analysis of the tomato transcription factor SlDof1 reveals its regulatory impacts on fruit ripening. Molecular Horticulture, 1: 9.

2020

Peiwen Wang#, Yuying Wang#, Weihao Wang, Tong Chen, Shiping Tian, Guozheng Qin*2020. Ubiquitination of phytoene synthase 1 precursor modulates carotenoid biosynthesis in tomato.  Communications Biology, 3: 730.

2019

Leilei Zhou, Shiping Tian*, Guozheng Qin*. 2019. RNA methylomes reveal the m6A-mediated regulation of DNA demethylase gene SlDML2 in tomato fruit ripening. Genome Biology, 20: 156.

Hua Li, Shiping Tian, Guozheng Qin*. 2019. NADPH oxidase is crucial for the cellular redox homeostasis in fungal pathogen Botrytis cinereaMolecular Plant-Microbe Interactions, 32: 1508-1516.

Jiangkuo Li, Hua Li, Sufeng Ji, Tong Chen, Shiping Tian, Guozheng Qin*. Enhancement of biocontrol ecacy of Cryptococcus laurentii by cinnamic acid against Penicillium italicum in citrus fruit. Postharvest Biology and Technology, 149: 42-49.

2018

Jianghua Cai, Peiwen Wang, Shiping Tian, Guozheng Qin*. 2018. Quantitative proteomic analysis reveals the involvement of mitochondrial proteins in tomato fruit ripening. Postharvest Biology and Technology, 145: 213-221.

Jianghua Cai#, Guozheng Qin#, Tong Chen, Shiping Tian*. 2018. The mode of action of remorin1 in regulating fruit ripening at transcriptional and post-transcriptional levels. New Phytologist, 219: 1406-1420

2017

Weihao Wang, Jianghua Cai, Peiwen Wang, Shiping Tian, Guozheng Qin*2017. Post-transcriptional regulation of fruit ripening and disease resistance in tomato by the vacuolar protease SlVPE3. Genome Biology, 18:47.

2016

Guozheng Qin#, Zhu Zhu#, Weihao Wang, Jianghua Cai, Yong Chen, Li Li, Shiping Tian*.2016. A Tomato vacuolar invertase inhibitor mediates sucrose metabolism and influences fruit ripening. Plant Physiology, 172:1596-1611.

2015

Jianghua Cai, Jian Chen, Guibin Lu, Yuming Zhao, Shiping Tian, Guozheng Qin*. 2015. Control of brown rot on jujube and peach fruit by trisodium phosphate. Postharvest Biology and Technology, 99: 93-98.

2014

Yuying Wang#, Weihao Wang#, Jianghua Cai, Yanrui Zhang, Guozheng Qin*. 2014. Shiping Tian*. Tomato nuclear proteome reveals the involvement of specific E2 ubiquitin-conjugating enzymes in fruit ripening. Genome Biology, 15:548.

Zhanquan Zhang#Guozheng Qin#, Boqiang Li, Shiping Tian*2014. Knocking out Bcsas1 in Botrytis cinerea impacts growth, development, and secretion of extracellular proteins which decreases virulence. Molecular Plant-Microbe Interactions, 27: 590-600.

2012

Baohua Cao, Jia Liu, Guozheng Qin*, Shiping Tian*2012. Oxidative stress acts on special membrane proteins to reduce the viability of Pseudomonas syringae pv. tomato. Journal of Proteome Research, 11: 4927-4938.

Baohua Cao, Hua Li, Shiping Tian, Guozheng Qin*. 2012. Boron improves the biocontrol activity of Cryptococcus laurentii against Penicillium expansum in jujube fruit. Postharvest Biology and Technology, 68: 16-21.

Zhanquan Zhang, Shiping Tian, Zhu Zhu, Yong Xu, Guozheng Qin*2012. Effects of 1-methylcyclopropene (1-MCP) on ripening and resistance of jujube (Zizyphus jujuba cv. Huping) fruit against postharvest disease. LWT–Food Science and Technology, 45: 13-19.

Guozheng Qin#*, Yuying Wang#, Baohua Cao, Weihao Wang, Shiping Tian*2012. Unraveling the regulatory network of MADS-box transcription factor RIN in fruit ripening. Plant Journal, 70: 243-255.

2011

Guozheng Qin#*, Jia Liu#, Baohua Cao, Boqiang Li, Shiping Tian*2011. Hydrogen peroxide acts on sensitive mitochondrial proteins to induce death of a fungal pathogen revealed by proteomic analysis. PLoS One, 6: e21945.

2010年及以前

Guozheng Qin, Yuanyuan Zong, Qiling Chen, Donglai Hua, Shiping Tian*. 2010. Inhibitory effect of boron against Botrytis cinerea on table grapes and its possible mechanisms of action. International Journal of Food Microbiology, 138: 145-150.

Guozheng Qin#, Xianghong Meng#, Qing Wang, Shiping Tian*2009. Oxidative damage of mitochondrial proteins contributes to fruit senescence: A redox proteomics analysis. Journal of Proteome Research, 8: 2449-2462.

Guozheng Qin#, Qing Wang#, Jia Liu, Boqiang Li, Shiping Tian*2009. Proteomic analysis of changes in mitochondrial protein expression during fruit senescence. Proteomics, 9: 4241-4253.

Guozheng Qin, Shiping Tian*, Zhulong Chan, Boqiang Li. 2007. Crucial role of antioxidant proteins and hydrolytic enzymes in pathogenicity of Penicillium expansum. Molecular & Cellular Proteomics, 6: 425-438. 

获奖:
2013年国家技术发明奖二等奖(第3完成人)
2016年北京市科学技术奖二等奖(第2完成人)
2013年卢嘉锡青年人才奖