王晓华 副研究员 硕士生导师
电子邮箱：wangxh@ibcas.ac.cn
电话：010-62836203
课题组：植物干旱逆境适应及调控技术研究组
https://people.ucas.edu.cn/~combiol
个人简历：
1997-09--2001-07 山东农业大学 农学学士
2003-09--2007-07 中国科学院植物研究所 理学硕士
2007-09--2011-07 中国科学院植物研究所 理学博士
2011-07--至今 中国科学院植物研究所, 助理研究员、副研究员
主要研究内容：
1. 植物极端抗逆的进化和分子机制
以极端抗逆植物为材料，通过转录组、代谢组、基因组和比较基因组等方法，为揭示物种环境适应性进化和作物极端干旱耐受性状改良，提供基因资源和理论基础
2. 植物活细胞和单分子成像技术研究
通过建立适合植物细胞蛋白质的单分子研究方法，实现单个膜蛋白运动参数的精准分析，为植物细胞早期响应的机制研究奠定技术。运用图像处理与三维重建、图像建模与特征识别的深度学习技术，分子动力学等手段，从多个角度揭示植物响应逆境胁迫的早期响应特征和细胞稳态的调控机制。
主要发表论文（#共同第一作者，*通讯作者）：
1. Ling Tang, Yafeng Wang, Wenhe Wang, Xin Deng, Xiaohua Wang* Genome-wide identification of CrRLK1L gene family and desiccation-induced expression profiles in Boea hygrometrica. Current Plant Biology. 2022. 31:100256.
2. Ling Tang, Yang Li, Cheng Zhong, Xin Deng, Xiaohua Wang*. Plant sterol clustering correlates with membrane microdomains as revealed by optical and computational microscopy. Membranes. 2021. 11:747.
3. Yuqing Yang, Hao Liu, Xiaojuan Li, Xiaohua Wang*. Intracellular trafficking and imaging methods of membrane-bound transcription factors in plants. Critical Reviews in Plant Sciences. 2020. 39: 418-430.
4. Xiaohua Wang#, Kai Song#, Yang Li, Ling Tang, Xin Deng*. Single-molecule imaging and computational microscopy approaches clarify the mechanism of the dimerization and membrane interactions of green fluorescent protein. Int J Mol Sci. 2019. 20(6):1410.
5. Xiaohua Wang#, Xiaojuan# Li, Xin Deng, Doan-Trung Luu, Maurel Christophe and Jinxing Lin*. Single-molecule fluorescence imaging to quantify membrane protein dynamics and oligomerization in living plant cells. Nature Protocols. 2015. 10: 2054-2063.
6. Jingjing Xing, Xiaojuan Li, Xiaohua Wang, Xueqin Lv, Li Wang, Liang Zhang, Yingfang Zhu, Qian-Hua Shen, František Baluška, Jozef Samaj, Jinxing Lin*. Secretion of phospholipase Dδ functions as a regulatory mechanism in plant innate immunity. Plant Cell. 2019. 31: 3015–3032.
7. Kai Song, Yiqun Xue, Xiaohua Wang, Yinglang Wan, Xin Deng, Jinxing Lin*. A modified GFP facilitates counting membrane protein subunits by step-wise photobleaching in Arabidopsis. Journal of Plant Physiology. 2017. 213: 129-133.
8. Sen Lin, Yuanyuan Zhao, M Gosnery, Xin Deng, Xiaohua Wang, Jinxing Lin*. An effective and inducible system of TAL effector-mediated transcriptional repression in Arabidopsis. Molecular Plant. 2016. 9:1546–1549.
9. Yuanyuan Zhao, Sen Lin, Zongbo Qiu, Dechang Cao, Jialong Wen, Xin Deng, Xiaohua Wang, Jinxing Lin and Xiaojuan Li*. MicroRNA857 is involved in the regulation of secondary growth of vascular tissues in Arabidopsis. Plant Physiology. 2016. 169: 2539-2552.
10. Xiaojuan Li#, Xiaohua Wang#, Yong Yang, Ruili Li, Qihua He, Xiaohong Fang, Doan-Trung Luu, Maurel Christophe, Jinxing Lin*. Single-molecule analysis of PIP2;1 dynamics and partitioning reveals multiple modes of Arabidopsis plasma membrane aquaporin regulation. Plant Cell. 2011. 23: 3780-3797.
11. Xiaohua Wang, Yan Teng, Qinli Wang, Xiaojuan Li, Xianyong Sheng, Maozhong Zheng, Jozef Samaj, Frantisek Baluska and Jinxing Lin *. Imaging of dynamic secretory vesicles in living pollen tubes of Picea meyeri using evanescent wave microscopy. Plant Physiology 2006. 141: 1591-1603.